Dapsone and Leprosy
نویسندگان
چکیده
منابع مشابه
Malaria, leprosy and dapsone.
Although the preventive action of dapsone against P. falciparum malaria was known for many years, there was no report about the incidence of P. falciparum malaria in leprosy patients treated with dapsone, especially from areas of Southeast Asia where both leprosy and malaria are endemic. Therefore, two clinic-based malaria surveys were undertaken at a gap of 12 years, comprising 506 lepromatous...
متن کاملDapsone agranulocytosis in a leprosy patient.
Dapsone-induced agranulocytosis is a rare adverse effect. There are various reports of agranulocytosis in patients treated with dapsone for malaria prophylaxis and other dermatological diseases. However, this adverse reaction in leprosy is not often encountered. We describe agranulocytosis in a young patient who was taking dapsone (100 mg) for borderline-tuberculoid leprosy in a rural environment.
متن کاملLow dose dapsone therapy in lepromatous leprosy.
U n der the conditions of this s tudy, dapsone in d oses of 5 mg and 10 mg daily when ad ministered to p atients with lepromat ous leprosy is an ineffe ctive therapy in terms of killing and elimin ation of My co. leprae from human skin and b one marrow . A real danger of facili tating the emergence of resistant bacilli exists . Therefore , un til there is more evidence from long term therapeuti...
متن کاملTreatment of paucibacillary leprosy patients with dapsone and rifampicin.
Dapsone resistance is found worldwide (1,2) and resistance to other available drugs such as clofazamine (3) and rifampicin (4) also occurs. It is known that paucibacillary leprosy patients harbour <106 bacilli (5). However, the treatment of paucibacillary leprosy is of long duration. It is psychologically undesirable for a symptom-free, paucibacillary patient to receive therapy for a long perio...
متن کاملDapsone hypersensitivity syndrome among leprosy patients in China.
OBJECTIVE To Study the incidence and clinical characteristics of dapsone hypersensitivity syndrome (DHS) among MDT-treated leprosy patients from 2006 to 2009 in China. METHODS A retrospective survey was carried out throughout China using a specially designed questionnaire. RESULTS From 2006 to 2009, there were 63 new patients reported to have DHS with an incidence of 1.0%. Among these patie...
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ژورنال
عنوان ژورنال: Nature
سال: 1972
ISSN: 0028-0836,1476-4687
DOI: 10.1038/239130b0